Genes for module 209

LocusLinkNameP-valueDescription
4316MMP7<1e-14matrix metalloproteinase 7 (matrilysin, uterine).MMP-7; MPSL1; PUMP-1.matrix metalloproteinase 7 preproprotein.
2028ENPEP<1e-14glutamyl aminopeptidase (aminopeptidase A).APA; gp160.glutamyl aminopeptidase (aminopeptidase A).
4485MST1<1e-14macrophage stimulating 1 (hepatocyte growth factor-like).MSP; HGFL; NF15S2; D3F15S2; DNF15S2.macrophage stimulating 1 (hepatocyte growth factor-like).
5645PRSS2<1e-14protease, serine, 2 (trypsin 2).TRY2; TRY8; TRYP2.protease, serine, 2 preproprotein.
7176TPS1<1e-14tryptase, alpha.TPS2; alpha II.alpha tryptase I precursor.
3240HP<1e-14haptoglobin..haptoglobin.
1514CTSL<1e-14cathepsin L.MEP; CATL.cathepsin L preproprotein.
715C1R<1e-14complement component 1, r subcomponent..complement component 1, r subcomponent.
717C2<1e-14complement component 2.CO2.complement component 2 precursor.
7113TMPRSS2<1e-14transmembrane protease, serine 2.PRSS10.transmembrane protease, serine 2.
1513CTSK<1e-14cathepsin K (pycnodysostosis).PKND; CTS02; CTSO1; CTSO2; MGC23107.cathepsin K preproprotein.
3003GZMK<1e-14granzyme K (serine protease, granzyme 3; tryptase II).PRSS; TRYP2.granzyme K precursor.
165AEBP1<1e-14AE binding protein 1.ACLP.adipocyte enhancer binding protein 1 precursor.
341APOC1<1e-14apolipoprotein C-I..apolipoprotein C-I precursor.
4318MMP9<1e-14matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase).GELB; CLG4B.matrix metalloproteinase 9 preproprotein.
2147F2<1e-14coagulation factor II (thrombin).PT.coagulation factor II precursor.
344APOC2<1e-14apolipoprotein C-II..apolipoprotein C-II precursor.
4313MMP2<1e-14matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase).CLG4; CLG4A; TBE-1.matrix metalloproteinase 2 preproprotein.
3249HPN<1e-14hepsin (transmembrane protease, serine 1).TMPRSS1.hepsin (transmembrane protease, serine 1).
5340PLG<1e-14plasminogen..plasminogen.
1361CPB2<1e-14carboxypeptidase B2 (plasma, carboxypeptidase U).CPU; PCPB; TAFI.plasma carboxypeptidase B2 isoform b.
8309ACOX2<1e-14acyl-Coenzyme A oxidase 2, branched chain.BCOX; BRCOX; BRCACOX.acyl-Coenzyme A oxidase 2, branched chain.
3479IGF1<1e-14insulin-like growth factor 1 (somatomedin C).IGFI.insulin-like growth factor 1 (somatomedin C).Insulin-like growth factor I (somatomedin C); activates cell proliferation and differentiation; strongly similar to murine Igf1|Proteome
5320PLA2G2A3.12639e-13phospholipase A2, group IIA (platelets, synovial fluid).MOM1; PLA2B; PLA2L; PLA2S; PLAS1.phospholipase A2, group IIA (platelets, synovial fluid).
5652PRSS86.53699e-13protease, serine, 8 (prostasin).PROSTASIN.prostasin preproprotein.
1369CPN17.67386e-13carboxypeptidase N, polypeptide 1, 50kD.CPN; SCPN.carboxypeptidase N, polypeptide 1, 50kD precursor.
2161F121.67688e-12coagulation factor XII (Hageman factor).HAF.coagulation factor XII precursor.
716C1S2.07478e-12complement component 1, s subcomponent..complement component 1, s subcomponent.
6652SORD8.83915e-12sorbitol dehydrogenase.SORD1.sorbitol dehydrogenase.
5327PLAT1.06013e-11plasminogen activator, tissue.TPA; T-PA.plasminogen activator, tissue type isoform 3 precursor.
10406WFDC21.13772e-10WAP four-disulfide core domain 2.HE4; WAP5; dJ461P17.6.WAP four-disulfide core domain 2 isoform 5.
1510CTSE1.68114e-10cathepsin E..cathepsin E isoform b preproprotein.
5054SERPINE11.94774e-10serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1.PAI; PAI1; PAI-1; PLANH1.plasminogen activator inhibitor-1.
290ANPEP2.21604e-10alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150).CD13; LAP1; PEPN; gp150.membrane alanine aminopeptidase precursor.
345APOC31.17669e-09apolipoprotein C-III..apolipoprotein C-III precursor.
3002GZMB1.22301e-09granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1).HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1.granzyme B precursor.
5225PGC3.91103e-09progastricsin (pepsinogen C)..progastricsin (pepsinogen C).
4312MMP16.98068e-09matrix metalloproteinase 1 (interstitial collagenase).CLG; CLGN.matrix metalloproteinase 1 preproprotein.
3426IF8.61806e-09I factor (complement).FI.I factor (complement).
7076TIMP19.807e-09tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor).EPA; EPO; HCI; CLGI; TIMP.tissue inhibitor of metalloproteinase 1 precursor.
570BAAT1.10444e-08bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase).BAT; BACAT.bile acid Coenzyme A: amino acid N-acyltransferase.
5045FURIN4.37505e-08furin (paired basic amino acid cleaving enzyme).FUR; PACE; SPC1; PCSK3.furin preproprotein.
629BF5.12651e-08B-factor, properdin.GBG; CFAB; PBF2.complement factor B preproprotein.
4314MMP38.44429e-08matrix metalloproteinase 3 (stromelysin 1, progelatinase).SL-1; STMY; STR1; STMY1; TRANSIN.matrix metalloproteinase 3 preproprotein.
5641LGMN1.07248e-07legumain.LGMN1; PRSC1.legumain.
5336PLCG21.34323e-07phospholipase C, gamma 2 (phosphatidylinositol-specific)..phospholipase C, gamma 2 (phosphatidylinositol-specific).
1368CPM5.20858e-07carboxypeptidase M..carboxypeptidase M precursor.
2191FAP9.69073e-07fibroblast activation protein, alpha.FAPA; DPPIV; SEPRASE.fibroblast activation protein, alpha subunit.
4973OLR11.31422e-06oxidised low density lipoprotein (lectin-like) receptor 1.LOX1; SCARE1.oxidised low density lipoprotein (lectin-like) receptor 1.
5328PLAU1.84483e-06plasminogen activator, urokinase.UPA; URK.plasminogen activator, urokinase.
2592GALT2.09662e-06galactose-1-phosphate uridylyltransferase..galactose-1-phosphate uridylyltransferase isoform 3.
5342PLGL3.55445e-06plasminogen-like..plasminogen-like.
8858PROZ4.01391e-06protein Z, vitamin K-dependent plasma glycoprotein.PZ.protein Z, vitamin K-dependent plasma glycoprotein.
1520CTSS6.01983e-06cathepsin S.MGC3886.cathepsin S preproprotein.
834CASP17.37917e-06caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase).ICE; P45; IL1BC.caspase 1 isoform gamma precursor.
4322MMP131.58533e-05matrix metalloproteinase 13 (collagenase 3).CLG3.matrix metalloproteinase 13 preproprotein.
4321MMP125.80488e-05matrix metalloproteinase 12 (macrophage elastase).HME; MME.matrix metalloproteinase 12 preproprotein.
837CASP46.15365e-05caspase 4, apoptosis-related cysteine protease.TX; ICH-2; Mih1TX; ICEREL-II; ICErel-II; ICE(rel)II.caspase 4 isoform gamma precursor.
110980.000129271ZSIG13; MGC5107; PRSS23-PENDING.protease, serine, 23 precursor.
94760.000406082NAPA.pronapsin A.
2582GALE0.000536259galactose-4-epimerase, UDP-..UDP-galactose-4-epimerase.
5055SERPINB20.000704637serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2.PAI; PAI2; PLANH2; HsT1201.serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2.
4069LYZ0.000891796lysozyme (renal amyloidosis)..lysozyme precursor.
649BMP10.000941782bone morphogenetic protein 1.TLD.bone morphogenetic protein 1 isoform 6 precursor.
1359CPA30.0014731carboxypeptidase A3 (mast cell)..mast cell carboxypeptidase A3 precursor.
3990LIPC0.0015307lipase, hepatic.HL; HTGL; LIPH.lipase C precursor.
3988LIPA0.00182668lipase A, lysosomal acid, cholesterol esterase (Wolman disease).LAL; CESD.lipase A precursor.
10136ELA3A0.00223909elastase 3A, pancreatic (protease E).ELA3.elastase 3, pancreatic (protease E).
1636ACE0.00263128angiotensin I converting enzyme (peptidyl-dipeptidase A) 1.DCP; ACE1; DCP1; CD143; MGC26566.angiotensin I converting enzyme isoform 3 precursor.
3001GZMA0.00270619granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3).HFSP; CTLA3.granzyme A precursor.
51056LAP30.00336797leucine aminopeptidase 3.LAP; PEPS; LAPEP.leucine aminopeptidase.
2159F100.00476714coagulation factor X.FX; FXA.coagulation factor X precursor.
1075CTSC0.00873173cathepsin C.HMS; PLS; CPPI; DPP1; DPPI; PALS.cathepsin C isoform b precursor.
3158HMGCS20.009454463
3157HMGCS10.009873933
5698PSMB90.0100314proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2).LMP2; RING12.proteasome beta 9 subunit isoform 2 proprotein.
5624PROC0.0115132protein C (inactivator of coagulation factors Va and VIIIa)..protein C (inactivator of coagulation factors Va and VIIIa).
75130.0121227
4323MMP140.0143063matrix metalloproteinase 14 (membrane-inserted).MMP-X1; MTMMP1; MT1-MMP.matrix metalloproteinase 14 preproprotein.
10537UBD0.0176461ubiquitin D.FAT10.diubiquitin.
726CAPN50.0249365calpain 5.HTRA3; nCL-3.calpain 5.
9588PRDX60.0314756peroxiredoxin 6.PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; KIAA0106; MGC46173.peroxiredoxin 6.
1519CTSO0.0319449cathepsin O.CTSO1.cathepsin O preproprotein.
8754ADAM90.0364277a disintegrin and metalloproteinase domain 9 (meltrin gamma).MCMP; MDC9; Mltng; KIAA0021.a disintegrin and metalloproteinase domain 9 preproprotein.
5184PEPD0.040186peptidase D.MGC10905; PROLIDASE.Xaa-Pro dipeptidase.
824CAPN20.0416221calpain 2, (mII) large subunit.mCANP; CANPL2; CANPml.calpain 2, large subunit.
7941PLA2G70.0417572phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma).PAFAH; LDL-PLA2.phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma).
4738NEDD80.0448494neural precursor cell expressed, developmentally down-regulated 8.Nedd-8.neural precursor cell expressed, developmentally down-regulated 8.
5655KLK100.0449264kallikrein 10.NES1; PRSSL1.kallikrein 10 precursor.