Genes for module 223

LocusLinkNameP-valueDescription
3111HLA-DOA<1e-14major histocompatibility complex, class II, DO alpha.HLADZ; HLA-DNA; HLA-DZA.major histocompatibility complex, class II, DO alpha.Alpha chain of MHC class II molecule; contains alpha 1 and alpha 2 domains|Proteome
3481IGF2<1e-14insulin-like growth factor 2 (somatomedin A)..insulin-like growth factor 2.
567B2M<1e-14beta-2-microglobulin..beta-2-microglobulin precursor.
3627CXCL10<1e-14chemokine (C-X-C motif) ligand 10.C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10.small inducible cytokine B10 precursor.
6039RNASE6<1e-14ribonuclease, RNase A family, k6.RNS6; RNASEK6; RNasek6; RNase k6.ribonuclease, RNase A family, k6.
5155PDGFB<1e-14platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog).SIS; SSV; PDGF2; c-sis.platelet-derived growth factor beta isoform 2, preproprotein.
8804CREG<1e-14cellular repressor of E1A-stimulated genes.CREG1.cellular repressor of E1A-stimulated genes.
969CD69<1e-14CD69 antigen (p60, early T-cell activation antigen)..CD69 antigen (p60, early T-cell activation antigen).
973CD79A<1e-14CD79A antigen (immunoglobulin-associated alpha).IGA; MB-1.CD79A antigen isoform 2 precursor.
1839DTR<1e-14diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor).DTS; HBEGF; HEGFL.diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor).
684BST2<1e-14bone marrow stromal cell antigen 2..bone marrow stromal cell antigen 2.
3569IL6<1e-14interleukin 6 (interferon, beta 2).HGF; HSF; BSF2; IL-6; IFNB2.interleukin 6 (interferon, beta 2).
2266FGG<1e-14fibrinogen, gamma polypeptide..fibrinogen, gamma chain isoform gamma-B precursor.
3122HLA-DRA<1e-14major histocompatibility complex, class II, DR alpha.HLA-DRA1.major histocompatibility complex, class II, DR alpha precursor.
5156PDGFRA<1e-14platelet-derived growth factor receptor, alpha polypeptide.CD140A; PDGFR2.platelet-derived growth factor receptor alpha precursor.
3600IL15<1e-14interleukin 15.IL-15; MGC9721.interleukin 15 isoform 2 precursor.
4609MYC<1e-14v-myc myelocytomatosis viral oncogene homolog (avian).c-Myc.v-myc myelocytomatosis viral oncogene homolog.
3601IL15RA<1e-14interleukin 15 receptor, alpha..interleukin 15 receptor, alpha isoform 2.
962CD48<1e-14CD48 antigen (B-cell membrane protein).BCM1; BLAST; hCD48; mCD48; BLAST1; SLAMF2; MEM-102.CD48 antigen (B-cell membrane protein).
2244FGB<1e-14fibrinogen, B beta polypeptide..fibrinogen, beta chain preproprotein.
3240HP<1e-14haptoglobin..haptoglobin.
374AREG<1e-14amphiregulin (schwannoma-derived growth factor).AR; SDGF; CRDGF; MGC13647.amphiregulin preproprotein.
2896GRN<1e-14granulin.PEPI; PCDGF.granulin.Granulin; putative growth factor; cysteine rich, contains multiple granulin repeats|Proteome
8851CDK5R1<1e-14cyclin-dependent kinase 5, regulatory subunit 1 (p35).p23; p25; p35; CDK5R; NCK5A; CDK5P35; MGC33831; p35nck5a.cyclin-dependent kinase 5, regulatory subunit 1.
7433VIPR1<1e-14vasoactive intestinal peptide receptor 1.II; HVR1; RCD1; RDC1; VIPR; VIRG; VPAC1; PACAP-R-2.vasoactive intestinal peptide receptor 1.
3553IL1B<1e-14interleukin 1, beta.IL-1; IL1F2; IL1-BETA.interleukin 1, beta proprotein.
914CD2<1e-14CD2 antigen (p50), sheep red blood cell receptor.T11; SRBC.CD2 antigen (p50), sheep red blood cell receptor.
1909EDNRA<1e-14endothelin receptor type A.ETA; ETRA.endothelin receptor type A.Endothelin A receptor; binds endothelins, induces intracellular calcium flux and arachidonic acid accumulation; member of the G protein-coupled receptor family|Proteome
11025LILRB3<1e-14leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3.HL9; ILT5; LIR3; CD85A; LIR-3.leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3.
2919CXCL1<1e-14chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha).GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a.chemokine (C-X-C motif) ligand 1.
2014EMP3<1e-14epithelial membrane protein 3.YMP.epithelial membrane protein 3.
11027LILRA2<1e-14leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2.ILT1; LIR7; CD85H; LIR-7.leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2.
1316COPEB<1e-14core promoter element binding protein.GBF; ZF9; BCD1; CPBP; KLF6; PAC1; ST12.core promoter element binding protein.
6504SLAMF1<1e-14signaling lymphocytic activation molecule family member 1.SLAM; CDw150.signaling lymphocytic activation molecule family member 1.
3107HLA-C<1e-14major histocompatibility complex, class I, C.D6S204; HLA-JY3.major histocompatibility complex, class I, C precursor.
3127HLA-DRB5<1e-14major histocompatibility complex, class II, DR beta 5..major histocompatibility complex, class II, DR beta 5 precursor.
1601DAB2<1e-14disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila).DOC2; DOC-2.disabled homolog 2.
7076TIMP1<1e-14tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor).EPA; EPO; HCI; CLGI; TIMP.tissue inhibitor of metalloproteinase 1 precursor.
920CD4<1e-14CD4 antigen (p55)..CD4 antigen (p55).
3109HLA-DMB<1e-14major histocompatibility complex, class II, DM beta.RING7; D6S221E.major histocompatibility complex, class II, DM beta precursor.
10135<1e-14pre-B-cell colony-enhancing factor isoform b.
4689NCF4<1e-14neutrophil cytosolic factor 4, 40kDa.NCF; P40PHOX.neutrophil cytosolic factor 4 (40kD) isoform 2.
3638INSIG1<1e-14insulin induced gene 1.CL-6; MGC1405.insulin induced gene 1 isoform 3.
3669ISG20<1e-14interferon stimulated gene 20kDa.HEM45.interferon stimulated gene 20kDa.
7039TGFA<1e-14transforming growth factor, alpha..transforming growth factor, alpha.
27074LAMP3<1e-14lysosomal-associated membrane protein 3.LAMP; DCLAMP; TSC403; DC-LAMP.lysosomal-associated membrane protein 3.
3552IL1A<1e-14interleukin 1, alpha.IL1; IL-1A; IL1F1; IL1-ALPHA.interleukin 1, alpha proprotein.
6358CCL14<1e-14chemokine (C-C motif) ligand 14.CC-1; CC-3; CKb1; MCIF; NCC2; SY14; HCC-1; HCC-3; NCC-2; SCYL2; SCYA14.chemokine (C-C motif) ligand 14 isoform 2 precursor.
3491CYR61<1e-14cysteine-rich, angiogenic inducer, 61.CCN1; GIG1; IGFBP10.cysteine-rich, angiogenic inducer, 61.Growth factor-inducible immediate early protein; may be involved in embryogenesis and cell proliferation|Proteome
1440CSF3<1e-14colony stimulating factor 3 (granulocyte).GCSF; G-CSF; MGC45931.colony stimulating factor 3 isoform c.
2123EVI2A<1e-14ecotropic viral integration site 2A.EVDA; EVI2.ecotropic viral integration site 2A.
3561IL2RG<1e-14interleukin 2 receptor, gamma (severe combined immunodeficiency).IMD4; CD132; SCIDX; SCIDX1.interleukin 2 receptor, gamma chain, precursor.
9308CD83<1e-14CD83 antigen (activated B lymphocytes, immunoglobulin superfamily).BL11; HB15.CD83 antigen (activated B lymphocytes, immunoglobulin superfamily).
926CD8B1<1e-14CD8 antigen, beta polypeptide 1 (p37).Ly3; CD8B; LYT3; Leu2.CD8 antigen beta polypeptide 1 isoform 6 precursor.
4061LY6E<1e-14lymphocyte antigen 6 complex, locus E.RIGE; SCA2; RIG-E; SCA-2; TSA-1.lymphocyte antigen 6 complex, locus E.
3783KCNN4<1e-14potassium intermediatesmall conductance calcium-activated channel, subfamily N, member 4.IK1; SK4; KCA4; hSK4; IKCA1; hKCa4; KCa3.1; hIKCa1.intermediate conductance calcium-activated potassium channel protein 1.
3976LIF<1e-14leukemia inhibitory factor (cholinergic differentiation factor).CDF; HILDA; D-FACTOR.leukemia inhibitory factor (cholinergic differentiation factor).
3105HLA-A<1e-14major histocompatibility complex, class I, A..major histocompatibility complex, class I, A precursor.
2012EMP1<1e-14epithelial membrane protein 1.TMP; CL-20.epithelial membrane protein 1.
942CD86<1e-14CD86 antigen (CD28 antigen ligand 2, B7-2 antigen).B70; B7-2; LAB72; CD28LG2; MGC34413.CD86 antigen isoform 2 precursor.
1906EDN11.42109e-13endothelin 1.ET1.endothelin 1.
4070TACSTD22.58638e-12tumor-associated calcium signal transducer 2.M1S1; EGP-1; GA733; TROP2; GA733-1.tumor-associated calcium signal transducer 2 precursor.
7176TPS19.57812e-12tryptase, alpha.TPS2; alpha II.alpha tryptase I precursor.
4192MDK1.81046e-11midkine (neurite growth-promoting factor 2).NEGF2.midkine (neurite growth-promoting factor 2).
4035LRP13.5385e-11low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor).APR; LRP; A2MR; CD91; APOER.low density lipoprotein-related protein 1.
694BTG14.02736e-11B-cell translocation gene 1, anti-proliferative..B-cell translocation protein 1.
2028ENPEP4.16946e-11glutamyl aminopeptidase (aminopeptidase A).APA; gp160.glutamyl aminopeptidase (aminopeptidase A).
3479IGF17.85292e-11insulin-like growth factor 1 (somatomedin C).IGFI.insulin-like growth factor 1 (somatomedin C).Insulin-like growth factor I (somatomedin C); activates cell proliferation and differentiation; strongly similar to murine Igf1|Proteome
8644AKR1C31.02403e-10aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II).DD3; HAKRB; HAKRe; HA1753; HSD17B5; hluPGFS; KIAA0119.aldo-keto reductase family 1, member C3.
8829NRP11.89999e-10neuropilin 1.NRP; VEGF165R.neuropilin 1.
604BCL62.02448e-10B-cell CLLlymphoma 6 (zinc finger protein 51).BCL5; LAZ3; ZNF51.B-cell lymphoma 6 protein.
11006LILRB44.07937e-10leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4.HM18; ILT3; LIR5; CD85K; LIR-5.leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4.
1466CSRP24.47614e-10cysteine and glycine-rich protein 2.CRP2; LMO5.cysteine and glycine-rich protein 2.
921CD56.20076e-10CD5 antigen (p56-62).T1; LEU1.CD5 antigen (p56-62).
2621GAS67.68949e-10growth arrest-specific 6.AXSF; AXLLG.growth arrest-specific 6.
2641GCG1.27616e-09glucagon.GLP1; GLP2; GRPP.glucagon preproprotein.
1670DEFA52.83993e-09defensin, alpha 5, Paneth cell-specific.DEF5; HD-5.defensin, alpha 5, preproprotein.
6402SELL3.86987e-09selectin L (lymphocyte adhesion molecule 1).TQ1; LAM1; LNHR; LSEL; CD62L; LAM-1; LYAM1; Leu-8; PLNHR; hLHRc; LECAM1; Lyam-1.selectin L.
1435CSF17.22096e-09colony stimulating factor 1 (macrophage).MCSF; MGC31930.colony stimulating factor 1 isoform c precursor.
10990LILRB57.46931e-09leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5.LIR8; CD85C; LIR-8.leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5.Leukocyte Ig-like receptor B5; may play a role in regulation of immune responses; member of the immunoglobulin superfamily|Proteome
5473PPBP7.82418e-09pro-platelet basic protein (chemokine (C-X-C motif) ligand 7).PBP; TGB; LDGF; MDGF; TGB1; CTAP3; CXCL7; NAP-2; SCYB7; THBGB; b-TG1; LA-PF4; THBGB1; Beta-TG; CTAPIII; NAP-2-L1.pro-platelet basic protein (includes platelet basic protein, bet.
2810SFN9.75453e-09stratifin..stratifin.
1441CSF3R1.06756e-08colony stimulating factor 3 receptor (granulocyte).CD114; GCSFR.colony stimulating factor 3 receptor isoform d precursor.
864RUNX31.32746e-08runt-related transcription factor 3.AML2; CBFA3; PEBP2aC.runt-related transcription factor 3.
5008OSM1.74236e-08oncostatin M.MGC20461.oncostatin M precursor.
3135HLA-G3.63467e-08HLA-G histocompatibility antigen, class I, G.TCA; HLA60; HLA-6.0.major histocompatibility complex, class I, G precursor.
4084MAD4.25158e-08MAX dimerization protein 1.MXD1.MAX dimerization protein 1.
4486MST1R7.90692e-08macrophage stimulating 1 receptor (c-met-related tyrosine kinase).RON; CDw136.macrophage stimulating 1 receptor (c-met-related tyrosine kinase).
3106HLA-B9.04276e-08major histocompatibility complex, class I, B..major histocompatibility complex, class I, B.
8781PSPHL9.73527e-08phosphoserine phosphatase-like.CO9..
975CD812.75954e-07CD81 antigen (target of antiproliferative antibody 1).S5.7; TAPA1.CD81 antigen.
7033TFF31.70726e-06trefoil factor 3 (intestinal).ITF; HITF.trefoil factor 3 (intestinal).
3134HLA-F3.46187e-06major histocompatibility complex, class I, F.HLAF; HLA-5.4; HLA-CDA12.major histocompatibility complex, class I, F precursor.
5052PRDX19.07428e-06peroxiredoxin 1.PAG; PAGA; PAGB; MSP23; NKEFA; TDPX2.peroxiredoxin 1.
7045TGFBI9.89233e-06transforming growth factor, beta-induced, 68kDa.CSD; CDB1; CSD1; CSD2; CSD3; LCD1; BIGH3; CDGG1.transforming growth factor, beta-induced, 68kDa.
7096TLR11.19085e-05toll-like receptor 1.TIL; rsc786; KIAA0012; DKFZp547I0610; DKFZp564I0682.toll-like receptor 1.
925CD8A1.78852e-05CD8 antigen, alpha polypeptide (p32).CD8; MAL; p32; Leu2.CD8 antigen alpha polypeptide isoform 2 precursor.
2059EPS81.78914e-05epidermal growth factor receptor pathway substrate 8..epidermal growth factor receptor pathway substrate 8.
5968REG1B2.54193e-05regenerating islet-derived 1 beta (pancreatic stone protein, pancreatic thread protein).REGH; REGL; PSPS2; REGI-BETA.regenerating islet-derived 1 beta precursor.
9180OSMR2.74783e-05oncostatin M receptor.OSMRB.oncostatin M receptor.
8974P4HA23.92547e-05procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II..procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II.
4665NAB25.91358e-05NGFI-A binding protein 2 (EGR1 binding protein 2).MADER.NGFI-A binding protein 2.NGFI-A binding protein 2; transcriptional corepressor that interacts with NGFI-A|Proteome
1131CHRM39.18005e-05cholinergic receptor, muscarinic 3.HM3.cholinergic receptor, muscarinic 3.
2243FGA9.83197e-05fibrinogen, A alpha polypeptide..fibrinogen, alpha chain isoform alpha-E preproprotein.
2249FGF40.00020979fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene).HST; KFGF; HST-1; HSTF1; K-FGF; HBGF-4.fibroblast growth factor 4 precursor.
6374CXCL50.000215329chemokine (C-X-C motif) ligand 5.ENA78; SCYB5; ENA-78.chemokine (C-X-C motif) ligand 5.
5611DNAJC30.000246054DnaJ (Hsp40) homolog, subfamily C, member 3.P58; HP58; PRKRI; P58IPK; P58IPK HP58.DnaJ (Hsp40) homolog, subfamily C, member 3.
11065UBE2C0.000246558ubiquitin-conjugating enzyme E2C.UBCH10; dJ447F3.2.ubiquitin-conjugating enzyme E2C isoform 5.
2064ERBB20.000329483v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuroglioblastoma derived oncogene homolog (avian).NEU; NGL; HER2; TKR1; HER-2.v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuroglioblastoma derived oncogene homolog.Tyrosine kinase receptor, a component of IL-6 signalling through the MAP kinase pathway; similar to the EGF receptor|Proteome
5154PDGFA0.000418706platelet-derived growth factor alpha polypeptide.PDGF1.platelet-derived growth factor alpha isoform 2.
6285S100B0.000445563S100 calcium binding protein, beta (neural).NEF; S100.S100 calcium-binding protein, beta.
3606IL180.000720159interleukin 18 (interferon-gamma-inducing factor).IGIF; IL-18; IL-1g; IL1F4; MGC12320.interleukin 18 proprotein.
6403SELP0.000953193selectin P (granule membrane protein 140kDa, antigen CD62).CD62; GRMP; PSEL; CD62P; GMP140; PADGEM.selectin P precursor.
10099TM4SF80.00117914transmembrane 4 superfamily member 8.TM4-A; TSPAN-3.transmembrane 4 superfamily member 8 isoform 2.
6935TCF80.00130099transcription factor 8 (represses interleukin 2 expression).BZP; ZEB; ZEB1; AREB6; ZFHEP; NIL-2A; ZFHX1A; NIL-2-A.transcription factor 8 (represses interleukin 2 expression).
5764PTN0.00150652pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1).HARP; HBNF; HBGF8; NEGF1.pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1).
1396CRIP10.00169529cysteine-rich protein 1 (intestinal).CRHP; CRIP; CRP1.cysteine-rich protein 1 (intestinal).
8061FOSL10.00172025FOS-like antigen 1.FRA1; fra-1.FOS-like antigen 1.
3077HFE0.0019435hemochromatosis.HH; HFE1; HLA-H.hemochromatosis protein isoform 9 precursor.
2495FTH10.00227199ferritin, heavy polypeptide 1.FTH; FTHL6.ferritin, heavy polypeptide 1.
6464SHC10.00330216SHC (Src homology 2 domain containing) transforming protein 1.SHC; SHCA.SHC (Src homology 2 domain containing) transforming protein 1.Adaptor protein; couples activated growth factor receptors to a signaling pathway; contains an SH2 domain|Proteome
1950EGF0.00394119epidermal growth factor (beta-urogastrone).URG.epidermal growth factor (beta-urogastrone).
6695SPOCK0.00466112sparcosteonectin, cwcv and kazal-like domains proteoglycan (testican).TIC1; SPOCK1; TESTICAN.sparcosteonectin, cwcv and kazal-like domains proteoglycan precursor.
5176SERPINF10.00543705serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1.PEDF; EPC-1.serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1.
9450LY860.00680185lymphocyte antigen 86.MD-1; dJ80N2.1.MD-1, RP105-associated.
6232RPS270.00732794ribosomal protein S27 (metallopanstimulin 1).MPS1; MPS-1.ribosomal protein S27.
11024LILRA10.00865631leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1.LIR6; CD85I; LIR-6.leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1.
678ZFP36L20.00978245zinc finger protein 36, C3H type-like 2.BRF2; ERF2; ERF-2; TIS11D.butyrate response factor 2.
8744TNFSF90.0102367tumor necrosis factor (ligand) superfamily, member 9.4-1BB-L.tumor necrosis factor (ligand) superfamily, member 9.
586BCAT10.0135987branched chain aminotransferase 1, cytosolic.BCT1; ECA39; MECA39.branched chain aminotransferase 1, cytosolic.
6191RPS4X0.0187616ribosomal protein S4, X-linked.CCG2; SCAR; SCR10; DXS306.ribosomal protein S4, X-linked X isoform.
3562IL30.0215151interleukin 3 (colony-stimulating factor, multiple).IL-3; MCGF; MULTI-CSF.interleukin 3 precursor.
4043LRPAP10.0216716low density lipoprotein receptor-related protein associated protein 1.RAP; MRAP; A2RAP; HBP44; A2MRAP.low density lipoprotein receptor-related protein associated protein 1.
2069EREG0.0230063epiregulin.ER.epiregulin precursor.
3570IL6R0.0233806interleukin 6 receptor.CD126; IL6RA; IL-6R-1; IL-6R-alpha.interleukin 6 receptor isoform 2 precursor.
2925GRPR0.0235278gastrin-releasing peptide receptor..gastrin-releasing peptide receptor.
146ADRA1D0.0257324adrenergic, alpha-1D-, receptor.ADRA1; ADRA1A; ADRA1R.alpha-1D-adrenergic receptor.
2013EMP20.0298749epithelial membrane protein 2.XMP.epithelial membrane protein 2.
4524MTHFR0.03258195
823CAPN10.0354181calpain 1, (muI) large subunit.CANP; muCL; CANPL1; muCANP.calpain 1, large subunit.
9564BCAR10.0423012breast cancer anti-estrogen resistance 1.CAS; CRKAS; P130CAS; P130Cas.breast cancer anti-estrogen resistance 1.
3654IRAK10.0424529interleukin-1 receptor-associated kinase 1.IRAK; pelle.interleukin-1 receptor-associated kinase 1.