Genes for module 248

LocusLinkNameP-valueDescription
9610RIN1<1e-14Ras and Rab interactor 1..ras inhibitor RIN1.
8419BFSP24.26326e-13beaded filament structural protein 2, phakinin.CP47; CP49; LIFL-L; PHAKININ.phakinin.
1545CYP1B14.26326e-13cytochrome P450, family 1, subfamily B, polypeptide 1.CP1B; GLC3A.cytochrome P450, family 1, subfamily B, polypeptide 1.
1418CRYGA8.2423e-13crystallin, gamma A.CRYG1; CRYG5; CRY-g-A.crystallin, gamma A.
2202EFEMP15.65592e-12EGF-containing fibulin-like extracellular matrix protein 1.DHRD; DRAD; FBNL; MLVT; S1-5; FBLN3.EGF-containing fibulin-like extracellular matrix protein 1 isoform b.
4687NCF13.46461e-11neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1).NOXO2; p47phox.neutrophil cytosolic factor 1.
9021SOCS37.28448e-11suppressor of cytokine signaling 3.CIS3; Cish3; SSI-3; SOCS-3.suppressor of cytokine signaling 3.
22821RASA32.34564e-10RAS p21 protein activator 3.GAPIII; MGC46517; MGC47588; GAP1IP4BP.RAS p21 protein activator 3.
1301COL11A13.61723e-10collagen, type XI, alpha 1.STL2; COLL6.alpha 1 type XI collagen isoform C preproprotein.
2919CXCL15.51353e-10chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha).GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a.chemokine (C-X-C motif) ligand 1.
6461SHB3.29007e-09SHB (Src homology 2 domain containing) adaptor protein B..SHB (Src homology 2 domain containing) adaptor protein B.
6314SCA75.68102e-09spinocerebellar ataxia 7 (olivopontocerebellar atrophy with retinal degeneration).OPCA3; ADCAII.ataxin 7.
4068SH2D1A1.41271e-08SH2 domain protein 1A, Duncans disease (lymphoproliferative syndrome).LYP; SAP; XLP; DSHP; EBVS; IMD5; XLPD; MTCP1.SH2 domain protein 1A.
25794FSCN21.6995e-08fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus).RFSN; RP30.fascin 2.
6503SLA1.85366e-08Src-like-adaptor.SLA1; SLAP.Src-like-adaptor.
5957RCV12.20516e-08recoverin..recoverin.
5781PTPN113.18545e-08protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1).CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; PRO1847; SH-PTP2; SH-PTP3; MGC14433.protein tyrosine phosphatase, non-receptor type 11.
1741DLG34.02343e-08discs, large homolog 3 (neuroendocrine-dlg, Drosophila).NEDLG; SAP102; KIAA1232.synapse-associated protein 102.
5578PRKCA5.64767e-08protein kinase C, alpha.PKCA.protein kinase C, alpha.
1742DLG46.65576e-08discs, large homolog 4 (Drosophila).PSD95; SAP90.postsynaptic density protein 95.
4882NPR29.87193e-08natriuretic peptide receptor Bguanylate cyclase B (atrionatriuretic peptide receptor B).NPRB; ANPRB; GUC2B; NPRBi.natriuretic peptide receptor B precursor isoform b.
6775STAT41.4925e-07signal transducer and activator of transcription 4..signal transducer and activator of transcription 4.
7466WFS12.38582e-07Wolfram syndrome 1 (wolframin).WFS; WFRS; DFNA6; DFNA14; DFNA38; DIDMOAD; WOLFRAMIN.wolframin.
8651SOCS12.89117e-07suppressor of cytokine signaling 1.JAB; CIS1; SSI1; TIP3; CISH1; SSI-1; SOCS-1.suppressor of cytokine signaling 1.
27ABL22.92802e-07v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene).ARG; ABLL.v-abl Abelson murine leukemia viral oncogene homolog 2 isoform b.
3576IL82.95363e-07interleukin 8.K60; NAF; GCP1; IL-8; LECT; LUCT; NAP1; 3-10C; CXCL8; GCP-1; LYNAP; MDNCF; MONAP; NAP-1; SCYB8; TSG-1; AMCF-I; b-ENAP.interleukin 8 precursor.
1410CRYAB3.31278e-07crystallin, alpha B.CRYA2; CTPP2.crystallin, alpha B.
320APBA13.7083e-07amyloid beta (A4) precursor protein-binding, family A, member 1 (X11).X11; X11A; MINT1; D9S411E; X11ALPHA.amyloid beta A4 precursor protein-binding, family A, member 1.
23770FKBP85.18133e-07FK506 binding protein 8, 38kDa.FKBP38; FKBPr38.FK506-binding protein 8.
6121RPE657.36687e-07retinal pigment epithelium-specific protein 65kDa.LCA2; RP20.retinal pigment epithelium-specific protein 65kDa.
11075STMN28.66462e-07stathmin-like 2.SCG10; SGC10; SCGN10.superiorcervical ganglia, neural specific 10.
7288TULP21.25977e-06tubby like protein 2.TUBL2.tubby like protein 2.
5961RDS1.67701e-06retinal degeneration, slow.RP7; AVMD; PRPH; AOFMD; PRPH2.retinal degeneration slow protein.
7439VMD22.05603e-06vitelliform macular dystrophy (Best disease, bestrophin).BMD; BEST.vitelliform macular dystrophy (Best disease, bestrophin).
2241FER2.29192e-06fer (fpsfes related) tyrosine kinase (phosphoprotein NCP94).TYK3.fer (fpsfes related) tyrosine kinase (phosphoprotein NCP94).
5029P2RY22.52812e-06purinergic receptor P2Y, G-protein coupled, 2.P2U; HP2U; P2U1; P2UR; P2Y2; P2RU1; P2Y2R; MGC20088; MGC40010.purinergic receptor P2Y2.
7305TYROBP2.7866e-06TYRO protein tyrosine kinase binding protein.DAP12; KARAP; PLOSL.TYRO protein tyrosine kinase binding protein isoform 2 precursor.
2268FGR6.15107e-06Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog.SRC2; c-fgr; p55c-fgr.Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog.
8777MPDZ7.33919e-06multiple PDZ domain protein.MUPP1.multiple PDZ domain protein.
3983ABLIM17.64115e-06actin binding LIM protein 1.abLIM; LIMAB1; LIMATIN; KIAA0059.actin-binding LIM protein 1 isoform s.
1421CRYGD8.0861e-06crystallin, gamma D.CACA; CRYG4; cry-g-D.crystallin, gamma D.
6247RS18.60439e-06retinoschisis (X-linked, juvenile) 1.RS; XLRS1.retinoschisis (X-linked, juvenile) 1.
6011RHOK1.29609e-05rhodopsin kinase.RK; GRK1; GPRK1.rhodopsin kinase.Rhodopsin kinase; phosphorylates rhodopsin following stimulation by light, regulates desensitization of the G protein-coupled receptor rhodopsin|Proteome
8573CASK1.74171e-05calciumcalmodulin-dependent serine protein kinase (MAGUK family).LIN2.calciumcalmodulin-dependent serine protein kinase (MAGUK family).
85722.39826e-05LIM domain protein.
5588PRKCQ2.84771e-05protein kinase C, theta..protein kinase C, theta.
5590PRKCZ3.11702e-05protein kinase C, zeta.PKC2.protein kinase C, zeta.
3000GUCY2D3.90256e-05guanylate cyclase 2D, membrane (retina-specific).LCA; LCA1; CORD6; GUC2D; retGC; GUC1A4; RETGC-1; ROS-GC1.guanylate cyclase 2D, membrane (retina-specific).
9826ARHGEF114.81733e-05Rho guanine nucleotide exchange factor (GEF) 11.GTRAP48; KIAA0380; PDZ-RHOGEF.Rho guanine nucleotide exchange factor (GEF) 11 isoform 2.
5158PDE6B5.99522e-05phosphodiesterase 6B, cGMP-specific, rod, beta (congenital stationary night blindness 3, autosomal dominant).PDEB; CSNB3.phosphodiesterase 6B, cGMP-specific, rod, beta.
2977GUCY1A26.847e-05guanylate cyclase 1, soluble, alpha 2.GC-SA2; GUC1A2.guanylate cyclase 1, soluble, alpha 2.
5545PRB49.60051e-05proline-rich protein BstNI subfamily 4.Po.proline-rich protein BstNI subfamily 4 precursor.
5582PRKCG9.84685e-05protein kinase C, gamma.PKCC; PKCG; SCA14.protein kinase C, gamma.
6773STAT20.000106544signal transducer and activator of transcription 2, 113kDa.P113; ISGF-3; STAT113; MGC59816.signal transducer and activator of transcription 2.
9595PSCDBP0.000147434pleckstrin homology, Sec7 and coiled-coil domains, binding protein.HE; B3-1; CYBR.pleckstrin homology, Sec7 and coiled-coil domains, binding protein.
5076PAX20.000150436paired box gene 2..paired box protein 2 isoform e.
5576PRKAR2A0.000197816protein kinase, cAMP-dependent, regulatory, type II, alpha.PRKAR2.protein kinase, cAMP-dependent, regulatory, type II, alpha.Type II regulatory alpha subunit of cAMP-dependent protein kinase; important for sperm motility, may mediate attachment of PKA to sperm flagella|Proteome
10461MERTK0.000218408c-mer proto-oncogene tyrosine kinase.mer; C-MER; c-mer.c-mer proto-oncogene tyrosine kinase.
3702ITK0.000235798IL2-inducible T-cell kinase.EMT; LYK; PSCTK2.IL2-inducible T-cell kinase.
1606DGKA0.000242775diacylglycerol kinase, alpha 80kDa.DAGK; DAGK1; DGK-alpha.diacylglycerol kinase, alpha 80kDa.
7287TULP10.000274345tubby like protein 1.RP14; TUBL1.tubby like protein 1.
7045TGFBI0.000278684transforming growth factor, beta-induced, 68kDa.CSD; CDB1; CSD1; CSD2; CSD3; LCD1; BIGH3; CDGG1.transforming growth factor, beta-induced, 68kDa.
5777PTPN60.000296449protein tyrosine phosphatase, non-receptor type 6.HCP; HCPH; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1.protein tyrosine phosphatase, non-receptor type 6 isoform 3.
1415CRYBB20.00035232crystallin, beta B2.CCA2; CRYB2; CRYB2A; D22S665.crystallin, beta B2.
5774PTPN30.000360348protein tyrosine phosphatase, non-receptor type 3.PTPH1.protein tyrosine phosphatase, non-receptor type 3.
2888GRB140.000435903growth factor receptor-bound protein 14..growth factor receptor-bound protein 14.
94110.000509063PTPL1-associated RhoGAP 1.
5082PDCL0.000561434phosducin-like.PhLP; DKFZp564M1863.phosducin-like.
673BRAF0.000600481v-raf murine sarcoma viral oncogene homolog B1.BRAF1; RAFB1.v-raf murine sarcoma viral oncogene homolog B1.
3716JAK10.000651189Janus kinase 1 (a protein tyrosine kinase).JAK1A.janus kinase 1.
1261CNGA30.000659233cyclic nucleotide gated channel alpha 3.CNG3; ACHM2; CCNC1; CCNCa; CNCG3; CCNCalpha.cyclic nucleotide gated channel alpha 3.
106030.00072829adaptor protein with pleckstrin homology and src homology 2 domains.
6645SNTB20.00077438syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2).SNT3; SNTL; SNT2B2; EST25263; D16S2531E.basic beta 2 syntrophin isoform b.
1124CHN20.00108122chimerin (chimaerin) 2.ARHGAP3; RHOGAP3.chimerin (chimaerin) 2.
114ADCY80.00113893adenylate cyclase 8 (brain).ADCY3; HBAC1.adenylate cyclase 8.
7399USH2A0.00151291Usher syndrome 2A (autosomal recessive, mild).US2; USH2.usherin.
2986GUCY2F0.00191128guanylate cyclase 2F, retinal.GC-F; GUC2F; GUC2DL; RETGC-2; ROS-GC2.guanylate cyclase 2F.
5335PLCG10.00191826phospholipase C, gamma 1 (formerly subtype 148).PLC1; PLC-II; PLC148.phospholipase C gamma 1 isoform b.
4060LUM0.00194234lumican.LDC; SLRR2D.lumican.
357APXL0.00198388apical protein-like (Xenopus laevis).HSAPXL.apical protein of Xenopus-like.
3269HRH10.00221344histamine receptor H1.H1-R; hisH1.histamine receptor H1.
272950.00229578alpha-actinin-2-associated LIM protein.Highly similar to murine Ril; contains a PDZ (DHR, GLGF) domain and a LIM domain|Proteome
2242FES0.00239226feline sarcoma oncogene.FPS.V-FES feline sarcoma viralV-FPS fujinami avian sarcoma viral oncogene homolog.
5296PIK3R20.00283194phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta).P85B; p85-BETA.phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta).
5264PHYH0.00289721phytanoyl-CoA hydroxylase (Refsum disease).PAHX.phytanoyl-CoA hydroxylase precursor.
5583PRKCH0.00304401protein kinase C, eta.PKCL; PKC-L; PRKCL; MGC5363.protein kinase C, eta.Eta isoform of protein_kinase_C; binds phorbol esters|Proteome
3718JAK30.00320566Janus kinase 3 (a protein tyrosine kinase, leukocyte).JAKL; LJAK.Janus kinase 3.
2009EML10.00332282echinoderm microtubule associated protein like 1.EMAP; ELP79; EMAPL; HuEMAP.echinoderm microtubule associated protein like 1.
5654PRSS110.00352375protease, serine, 11 (IGF binding).L56; HtrA; HTRA1; ORF480.protease, serine, 11.
8825LIN7A0.00369267lin-7 homolog A (C. elegans).LIN7; VELI1; LIN-7A; MALS-1; TIP-33.lin-7 homolog A.
5587PRKCM0.00375763protein kinase C, mu.PKD; PKCM; PKC-MU.protein kinase C, mu.
2200FBN10.0040552fibrillin 1 (Marfan syndrome).FBN; SGS; MASS; MFS1; OCTD.fibrillin 1.
2984GUCY2C0.00443915guanylate cyclase 2C (heat stable enterotoxin receptor).STAR; GUC2C.guanylate cyclase 2C (heat stable enterotoxin receptor).
3859KRT120.0045308keratin 12 (Meesmann corneal dystrophy).K12.keratin 12 (Meesmann corneal dystrophy).
8526DGKE0.00470474diacylglycerol kinase, epsilon 64kDa.DGK; DAGK6.diacylglycerol kinase epsilon.
4653MYOC0.00558756myocilin, trabecular meshwork inducible glucocorticoid response.GPOA; JOAG; TIGR; GLC1A.myocilin.
3579IL8RB0.00631249interleukin 8 receptor, beta.CXCR2; IL8R2; IL8RA; CMKAR2; CDw128b.interleukin 8 receptor beta.
2886GRB70.00638293growth factor receptor-bound protein 7..growth factor receptor-bound protein 7.Growth factor receptor-bound protein 7; contains an SH2 domain|Proteome
10692RRH0.00680211retinal pigment epithelium-derived rhodopsin homolog..peropsin.
6004RGS160.00805022regulator of G-protein signalling 16.RGS-R; A28-RGS14; A28-RGS14P.regulator of G-protein signalling 16.
5288PIK3C2G0.0084383phosphoinositide-3-kinase, class 2, gamma polypeptide.PI3K-C2GAMMA.phosphoinositide-3-kinase, class 2, gamma polypeptide.
4842NOS10.00852214nitric oxide synthase 1 (neuronal).NOS.nitric oxide synthase 1 (neuronal).
1827DSCR10.00870819Down syndrome critical region gene 1.CSP1; MCIP1; ADAPT78.Down syndrome critical region protein 1.
100090.0100094WUGSC:H_DJ525N14.1.kaiso.
2780GNAT20.0107875guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.GNATC.guanine nucleotide binding protein, alpha transducing activity polypeptide 2.
7294TXK0.0131631TXK tyrosine kinase.RLK; TKL; BTKL; PTK4; PSCTK5.TXK tyrosine kinase.
5080PAX60.0139129paired box gene 6 (aniridia, keratitis).AN; AN2; MGDA; WAGR; D11S812E.paired box gene 6 isoform b.
5306PITPN0.0154333phosphotidylinositol transfer protein.VIB1A; PITPNA.phosphotidylinositol transfer protein, alpha.
5664PSEN20.0164987presenilin 2 (Alzheimer disease 4).AD4; PS2; AD3L; STM2.presenilin 2 isoform 2.
24139EML20.0168157echinoderm microtubule associated protein like 2.ELP70; EMAP2; EMAP-2.echinoderm microtubule associated protein like 2.
3617IMPG10.017252interphotoreceptor matrix proteoglycan 1.IPM150.interphotoreceptor matrix proteoglycan 1.
2887GRB100.0199367growth factor receptor-bound protein 10.RSS; IRBP; MEG1; GRB-IR; KIAA0207..
8412BCAR30.0206823breast cancer anti-estrogen resistance 3.NSP2; SH2D3B.breast cancer antiestrogen resistance 3.
7525YES10.0209661v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1.Yes; C-YES; c-yes; HsT441; P61-YES.viral oncogene yes-1 homolog 1.
1259CNGA10.0217039cyclic nucleotide gated channel alpha 1.CNCG; CNG1; CNCG1; RCNC1; RCNCa; RCNCalpha.cyclic nucleotide gated channel alpha 1.
4354MPP10.025143membrane protein, palmitoylated 1, 55kDa.PEMP; EMP55; DXS552; DXS552E.palmitoylated membrane protein 1.
9402GRAP20.0253055GRB2-related adaptor protein 2.P38; GADS; GRID; GRPL; GrbX; Mona; GRB2L; GRBLG; Grf40; GRAP-2.GRB2-related adaptor protein 2.
10497UNC13B0.0255827unc-13 homolog B (C. elegans).UNC13; MUNC13; Unc13h2; hmunc13.UNC13 (C. elegans)-like.
5341PLEK0.0257462pleckstrin.P47.pleckstrin.
5145PDE6A0.0277409phosphodiesterase 6A, cGMP-specific, rod, alpha.PDEA; CGPR-A.phosphodiesterase 6A, alpha subunit.
369ARAF10.0295271v-raf murine sarcoma 3611 viral oncogene homolog 1.PKS2; A-RAF; RAFA1.v-raf murine sarcoma 3611 viral oncogene homolog 1.
7409VAV10.0297772vav 1 oncogene.VAV.vav 1 oncogene.
5783PTPN130.0331979protein tyrosine phosphatase, non-receptor type 13 (APO-1CD95 (Fas)-associated phosphatase).PNP1; FAP-1; PTP1E; PTPL1; PTPLE; PTP-BL; PTP-BAS.protein tyrosine phosphatase, non-receptor type 13 isoform 4.
6271S100A10.0338981S100 calcium binding protein A1.S100; S100A.S100 calcium binding protein A1.
3932LCK0.0347488lymphocyte-specific protein tyrosine kinase..lymphocyte-specific protein tyrosine kinase.
613BCR0.038763breakpoint cluster region.ALL; CML; PHL; BCR1; D22S11; D22S662.breakpoint cluster region isoform 2.
3603IL160.0391548interleukin 16 (lymphocyte chemoattractant factor).LCF; IL-16; prIL-16.interleukin 16 isoform 2.
1001CDH30.043083cadherin 3, type 1, P-cadherin (placental).CDHP; HJMD; PCAD.cadherin 3, type 1 preproprotein.
1428CRYM0.0458973crystallin, mu.THBP; DFNA40.crystallin, mu.