| Regulator | Module | Description | Genes |
| AFR1 | 43 | Unknown genes I | 36 |
| ALPHA2 | 12 | Nuclear | 47 |
| ALPHA2 | 12 | Nuclear | 47 |
| ALPHA2 | 1 | Respiration and carbon regulation | 55 |
| APG1 | 44 | Unknown genes II | 29 |
| BAS1 | 5 | Glycolysis and Folding | 37 |
| BCY1 | 39 | Protein folding | 23 |
| BCY1 | 27 | Cell wall and transport I | 23 |
| BMH1 | 5 | Glycolysis and Folding | 37 |
| BMH1 | 39 | Protein folding | 23 |
| BMH2 | 37 | Proteasome and Endocytosis | 31 |
| CDC14 | 20 | TFs I | 53 |
| CDC14 | 30 | Cell cycle (G2/M) | 30 |
| CDC42 | 38 | Protein modification and trafficking | 62 |
| CLB1 | 30 | Cell cycle (G2/M) | 30 |
| CLB5 | 31 | Cell cycle, TFs and DNA metabolism | 71 |
| CMK1 | 33 | Mitochondrial and Signaling | 87 |
| CMK1 | 2 | Energy, osmolarity and cAMP signaling | 64 |
| CMK1 | 1 | Respiration and carbon regulation | 55 |
| CNB1 | 47 | Mixed III | 41 |
| CUP9 | 37 | Proteasome and Endocytosis | 31 |
| ECM22 | 5 | Glycolysis and Folding | 37 |
| FAR1 | 30 | Cell cycle (G2/M) | 30 |
| FKH1 | 48 | Mixed IV | 35 |
| GAC1 | 4 | Energy and Osmotic stress II | 42 |
| GAC1 | 6 | Galactose metabolism | 4 |
| GAC1 | 1 | Respiration and carbon regulation | 55 |
| GAL4 | 6 | Galactose metabolism | 4 |
| GAT1 | 9 | AA metabolism I | 39 |
| GAT1 | 8 | Nitrogen catabolite repression | 29 |
| GAT1 | 24 | Sporulation and TFs | 74 |
| GAT1 | 11 | AA and purine metabolism | 53 |
| GCN20 | 5 | Glycolysis and Folding | 37 |
| GCN20 | 36 | ER and Nuclear | 79 |
| GCN20 | 24 | Sporulation and TFs | 74 |
| GCN20 | 47 | Mixed III | 41 |
| GCN20 | 46 | Mixed II | 52 |
| GCN20 | 42 | Unkown (sub-telomeric) | 82 |
| GIS1 | 33 | Mitochondrial and Signaling | 87 |
| GIS1 | 31 | Cell cycle, TFs and DNA metabolism | 71 |
| GIS1 | 18 | TFs and RNA processing | 59 |
| GIS1 | 17 | DNA and RNA processing | 77 |
| HAP4 | 10 | AA metabolism II | 37 |
| HAP4 | 1 | Respiration and carbon regulation | 55 |
| HRT1 | 37 | Proteasome and Endocytosis | 31 |
| IME4 | 16 | RNA Processing and Cell Cycle | 59 |
| IME4 | 9 | AA metabolism I | 39 |
| IME4 | 37 | Proteasome and Endocytosis | 31 |
| IME4 | 32 | Cell cycle and general TFs | 64 |
| INO2 | 12 | Nuclear | 47 |
| KAR4 | 45 | Unknown genes III | 39 |
| KIN82 | 3 | Energy and Osmotic stress I | 31 |
| KIN82 | 28 | Cell wall and Transport II | 63 |
| KIN82 | 2 | Energy, osmolarity and cAMP signaling | 64 |
| KRE35 | 15 | mRNA, rRNA and tRNA processing | 43 |
| KSP1 | 20 | TFs I | 53 |
| MCM1 | 20 | TFs I | 53 |
| MET18 | 19 | TFs and nuclear transport | 48 |
| MRF1' | 35 | Trafficking and Mitochondrial | 87 |
| MSN4 | 26 | Sporulation and Cell wall | 78 |
| MSN4 | 28 | Cell wall and Transport II | 63 |
| MSN4 | 1 | Respiration and carbon regulation | 55 |
| NOT3 | 36 | ER and Nuclear | 79 |
| PLP2 | 8 | Nitrogen catabolite repression | 29 |
| PPH3 | 18 | TFs and RNA processing | 59 |
| PPH3 | 13 | Mixed I | 28 |
| PPT1 | 16 | RNA Processing and Cell Cycle | 59 |
| PPT1 | 14 | Ribosomal and phosphate metabolism | 32 |
| PPT1 | 14 | Ribosomal and phosphate metabolism | 32 |
| PPT1 | 15 | mRNA, rRNA and tRNA processing | 43 |
| PPT1 | 19 | TFs and nuclear transport | 48 |
| PPT1 | 2 | Energy, osmolarity and cAMP signaling | 64 |
| PPT1 | 43 | Unknown genes I | 36 |
| PPT1 | 17 | DNA and RNA processing | 77 |
| PTC3 | 38 | Protein modification and trafficking | 62 |
| PTC3 | 22 | TFs, cell wall and mating | 39 |
| RAS2 | 13 | Mixed I | 28 |
| RSC3 | 34 | Mitochondrial and Protein fate | 37 |
| SDS22 | 35 | Trafficking and Mitochondrial | 87 |
| SDS22 | 34 | Mitochondrial and Protein fate | 37 |
| SHO1 | 48 | Mixed IV | 35 |
| SHP1 | 27 | Cell wall and transport I | 23 |
| SIP2 | 14 | Ribosomal and phosphate metabolism | 32 |
| SIP2 | 25 | Sporulation and cAMP pathway | 59 |
| SIP2 | 46 | Mixed II | 52 |
| SKO1 | 40 | Oxidative stress I | 15 |
| TOS8 | 7 | Snf kinase regulated processes | 74 |
| TOS8 | 46 | Mixed II | 52 |
| TOS8 | 41 | Oxidative stress II | 15 |
| TPK1 | 33 | Mitochondrial and Signaling | 87 |
| TPK1 | 35 | Trafficking and Mitochondrial | 87 |
| TPK1 | 3 | Energy and Osmotic stress I | 31 |
| TPK1 | 2 | Energy, osmolarity and cAMP signaling | 64 |
| TPK1 | 17 | DNA and RNA processing | 77 |
| TPK2 | 16 | RNA Processing and Cell Cycle | 59 |
| TPK2 | 15 | mRNA, rRNA and tRNA processing | 43 |
| TUP1 | 36 | ER and Nuclear | 79 |
| UGA3 | 10 | AA metabolism II | 37 |
| UME1 | 32 | Cell cycle and general TFs | 64 |
| UME1 | 47 | Mixed III | 41 |
| USV1 | 38 | Protein modification and trafficking | 62 |
| USV1 | 16 | RNA Processing and Cell Cycle | 59 |
| USV1 | 4 | Energy and Osmotic stress II | 42 |
| USV1 | 7 | Snf kinase regulated processes | 74 |
| USV1 | 39 | Protein folding | 23 |
| USV1 | 19 | TFs and nuclear transport | 48 |
| USV1 | 26 | Sporulation and Cell wall | 78 |
| USV1 | 25 | Sporulation and cAMP pathway | 59 |
| USV1 | 29 | Cell differentiation | 41 |
| USV1 | 29 | Cell differentiation | 41 |
| USV1 | 28 | Cell wall and Transport II | 63 |
| WSC4 | 4 | Energy and Osmotic stress II | 42 |
| XBP1 | 10 | AA metabolism II | 37 |
| XBP1 | 25 | Sporulation and cAMP pathway | 59 |
| XBP1 | 32 | Cell cycle and general TFs | 64 |
| XBP1 | 3 | Energy and Osmotic stress I | 31 |
| XBP1 | 45 | Unknown genes III | 39 |
| XBP1 | 1 | Respiration and carbon regulation | 55 |
| YAP1 | 40 | Oxidative stress I | 15 |
| YAP1 | 40 | Oxidative stress I | 15 |
| YAP6 | 4 | Energy and Osmotic stress II | 42 |
| YAP6 | 7 | Snf kinase regulated processes | 74 |
| YAP6 | 26 | Sporulation and Cell wall | 78 |
| YER184C | 33 | Mitochondrial and Signaling | 87 |
| YER184C | 2 | Energy, osmolarity and cAMP signaling | 64 |
| YJL103C | 36 | ER and Nuclear | 79 |
| YPK1 | 29 | Cell differentiation | 41 |
| YPK1 | 34 | Mitochondrial and Protein fate | 37 |
| YPK2 | 39 | Protein folding | 23 |