Module 565 |
General Properties | |
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Below we list the number of gene sets from which the module was composed was originally composed, and the number of genes and experiments that it contains. Clicking on the number of genes will display a detailed list of all the genes in the module. Clicking on the number of experiments will display a detailed list of all the experiments in the module. | |
Num gene sets: | 5 |
Num genes: | 40 (see additional genes for this module) |
Num experiments: | 30 (12 induced, 18 repressed) |
Gene sets | |
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Below we list the gene sets from which the module was originally composed. Clicking on a gene set will display all the genes associated with that gene set. Also listed are all the other modules in which the gene set participates. | |
Whitfield02 18 | 386 565 |
Nuclear Receptors | 269 386 565 |
steroid hormone receptor activity | 142 269 386 565 |
ligand_dependent nuclear receptor activity | |
Whitfield02 40 | 565 |
Enriched clinical annotations | ||||
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For each of the clinical annotations, we tested whether it was enriched in the set of experiments in which the module is significantly induced (or repressed). Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of induced (or repressed) experiments in which they appear. We also show the fraction of experiments with the given annotation that are included in this module ('Hits (%)' column). Rows that correspond to annotations that were enriched in the induced experiments of the module have a red background, while rows corresponding to annotations enriched in the repressed experiments have a green background. For each annotation, we also list the other modules in which it was enriched. | ||||
Clinical annotation | P-value | Hits | Hits(%) | Modules |
AT/RT (CNS and not) | 8.86e-09 | 5 | 27.777 | 3 4 8 13 17 28 32 50 62 81 82 83 86 87 91 102 103 105 111 112 113 114 115 149 151 152 155 157 159 176 233 245 250 274 278 299 316 321 386 425 446 447 468 473 483 497 565 570 |
AT/RT CNS | 6.48e-06 | 3 | 16.666 | 111 113 157 274 386 446 468 497 565 570 |
Enriched GO annotations | ||||
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For each GO annotation, we tested whether it was enriched in the set of genes of the module. Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of genes in which they appear. We also show the fraction of genes with the given GO annotation that are included in this module ('Hits (%)' column). |
Visual display | |||||||||
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Below is a visual display of the module. Shown are those arrays in which the module's genes significantly change, and the direction of change (induction/repression) in each array is indicated (middle, labeled 'Module changes'; red/green row). The arrays that correspond to the significant clinical attributes are also shown (top; brown rows). The gene sets that compose the module are also shown (left) along with an indication of the membership of the module genes in these gene sets. | |||||||||
You can also view the images within GeneXPress by loading the module gxp file file. | |||||||||
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