Module 446 |
General Properties | |
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Below we list the number of gene sets from which the module was composed was originally composed, and the number of genes and experiments that it contains. Clicking on the number of genes will display a detailed list of all the genes in the module. Clicking on the number of experiments will display a detailed list of all the experiments in the module. | |
Num gene sets: | 2 |
Num genes: | 17 (see 210 additional genes for this module) |
Num experiments: | 107 (22 induced, 85 repressed) |
Gene sets | |
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Below we list the gene sets from which the module was originally composed. Clicking on a gene set will display all the genes associated with that gene set. Also listed are all the other modules in which the gene set participates. | |
coreceptor activity | 446 570 |
cell differentiation | 446 570 |
Enriched GO annotations | ||||
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For each GO annotation, we tested whether it was enriched in the set of genes of the module. Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of genes in which they appear. We also show the fraction of genes with the given GO annotation that are included in this module ('Hits (%)' column). | ||||
GO annotation | P-value | Hits | Hits(%) | |
coreceptor activity | 1.60e-23 | 9 | 52.941 | |
lymphocyte activation | 5.63e-19 | 11 | 64.705 | |
cell activation | 3.91e-15 | 9 | 52.941 | |
cell differentiation | 4.48e-15 | 9 | 52.941 | |
immune response | 1.83e-14 | 13 | 76.470 | |
response to biotic stimulus | 1.30e-10 | 11 | 64.705 | |
defense response | 1.90e-10 | 10 | 58.823 | |
chemokine receptor activity | 1.03e-08 | 4 | 23.529 | |
MHC protein binding | 1.64e-07 | 3 | 17.647 | |
organogenesis | 2.12e-07 | 8 | 47.058 | |
morphogenesis | 4.36e-07 | 8 | 47.058 | |
chemokine binding | 9.79e-07 | 3 | 17.647 | |
development | 1.12e-06 | 9 | 52.941 | |
chemotaxis | 1.37e-06 | 5 | 29.411 | |
peptide receptor activity | 4.31e-06 | 4 | 23.529 | |
cellular defense response | 5.00e-06 | 4 | 23.529 | |
receptor activity | 7.52e-06 | 9 | 52.941 | |
T-cell activation | 9.18e-06 | 3 | 17.647 | |
response to pest/pathogen/parasite | 9.48e-06 | 6 | 35.294 | |
transmembrane receptor protein tyrosine kinase signaling pathway | 1.22e-05 | 4 | 23.529 | |
signal transducer activity | 1.49e-05 | 11 | 64.705 | |
inflammatory response | 3.09e-05 | 5 | 29.411 | |
neurogenesis | 5.72e-05 | 5 | 29.411 |
Visual display | |||||||||
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Below is a visual display of the module. Shown are those arrays in which the module's genes significantly change, and the direction of change (induction/repression) in each array is indicated (middle, labeled 'Module changes'; red/green row). The arrays that correspond to the significant clinical attributes are also shown (top; brown rows). The gene sets that compose the module are also shown (left) along with an indication of the membership of the module genes in these gene sets. | |||||||||
You can also view the images within GeneXPress by loading the module gxp file file. | |||||||||
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