Module 487 |
General Properties | |
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Below we list the number of gene sets from which the module was composed was originally composed, and the number of genes and experiments that it contains. Clicking on the number of genes will display a detailed list of all the genes in the module. Clicking on the number of experiments will display a detailed list of all the experiments in the module. | |
Num gene sets: | 2 |
Num genes: | 11 (see 1177 additional genes for this module) |
Num experiments: | 80 (17 induced, 63 repressed) |
Gene sets | |
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Below we list the gene sets from which the module was originally composed. Clicking on a gene set will display all the genes associated with that gene set. Also listed are all the other modules in which the gene set participates. | |
regulation of G_protein coupled receptor protein signaling pathway | |
lipid biosynthesis | 487 |
Enriched GO annotations | ||||
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For each GO annotation, we tested whether it was enriched in the set of genes of the module. Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of genes in which they appear. We also show the fraction of genes with the given GO annotation that are included in this module ('Hits (%)' column). | ||||
GO annotation | P-value | Hits | Hits(%) | |
regulation of G-protein coupled receptor protein signaling pathway | 1.17e-25 | 9 | 81.818 | |
G-protein coupled receptor protein signaling pathway | 6.17e-12 | 9 | 81.818 | |
cell surface receptor linked signal transduction | 2.42e-11 | 9 | 81.818 | |
GTPase activator activity | 1.00e-09 | 5 | 45.454 | |
GTPase regulator activity | 7.88e-08 | 5 | 45.454 | |
cell growth | 8.53e-08 | 8 | 72.727 | |
cell communication | 8.69e-08 | 9 | 81.818 | |
signal transduction | 4.00e-07 | 9 | 81.818 | |
regulation of cellular process | 1.59e-06 | 8 | 72.727 | |
transcription regulator activity | 4.57e-06 | 8 | 72.727 | |
regulation of biological process | 1.32e-05 | 8 | 72.727 | |
enzyme regulator activity | 2.42e-05 | 5 | 45.454 | |
signal transducer activity | 6.94e-05 | 8 | 72.727 | |
calmodulin binding | 7.58e-05 | 3 | 27.272 |
Visual display | |||||||||
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Below is a visual display of the module. Shown are those arrays in which the module's genes significantly change, and the direction of change (induction/repression) in each array is indicated (middle, labeled 'Module changes'; red/green row). The arrays that correspond to the significant clinical attributes are also shown (top; brown rows). The gene sets that compose the module are also shown (left) along with an indication of the membership of the module genes in these gene sets. | |||||||||
You can also view the images within GeneXPress by loading the module gxp file file. | |||||||||
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